Rib-X Pharmaceuticals to Present at the 49th ICAAC
Rib-X Pharmaceuticals, Inc. ("Rib-X" or the "Company"), a development-stage company focused on the discovery, development and commercialization of novel antibiotics for the treatment of acute care antibiotic-resistant infections, today announced that seven posters have been accepted for presentation at the 49th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) taking place in San Francisco, CA, on September 12 - 15, 2009. Details on these presentations are as follows:
"It is very satisfying to present for critical review the scientific developments Rib-X has fostered during the past year and in four distinct antibiotic programs. It is expecially rewarding to receive input from our peers at the premier anti-infective conference," said Susan Froshauer, Ph.D., President and Chief Executive Officer, Rib-X Pharmaceuticals. "We are particularly pleased to present proof-of-concept data on our novel chemical class Gram-negative program."
About Rib-X Pharmaceuticals, Inc.
Rib-X Pharmaceuticals, Inc. is a product-driven small molecule drug discovery and development company focused on the structure-based design of new classes of antibiotics. The Company's underlying drug discovery engine capitalizes on its proprietary high-resolution crystal structure of the ribosome, which performs an essential role in protein synthesis. Many known, commercially valuable antibiotics exert their effects by binding to the bacterial ribosome. The Company's integrated research strategy, which combines state-of-the-art, proprietary computational analysis, X-ray crystallography, medicinal chemistry, microbiology and biochemistry, allows it to rapidly synthesize new agents designed to avoid typical antibiotic resistance mechanisms. Rib-X's iterative intelligent engine has yielded several distinctive new antibiotics, including radezolid, that can be used for the treatment of either community- or hospital-acquired infections. Rib-X has successfully completed Phase 2 trials with delafloxacin (RX-3341), a broad-spectrum fluoroquinolone with potent activity against quinolone-resistant Gram-positive bacteria, including MRSA. Radezolid (RX-1741), an oxazolidinone that was discovered at Rib-X as an oral/IV agent for treatment of serious Gram-positive infections, has completed two Phase 2 trials. The Rχ-04 discovery program is developing novel classes of antibiotics active against multi-drug resistant Gram-negative bacteria, and the Rχ-02 discovery program is focused on developing an IV/oral macrolide active against methicillin-resistant S. aureus, multidrug-resistant Streptococcus pneumoniae and S. pyogenes. Both delafloxacin and radezolid are currently in late-stage clinical trials.
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Gina Nugent
The Yates Network 617.460.3579 gina@theyatesnetwork.com |